2012

Specificity and complexity in genetic determinants of gene expression revealed by analysis of different primary immune cell types

Updated 25/03/2012

A major challenge in taking forward the results of recent genome-wide association studies of common disease has been how to identify specific functionally important genetic variants underlying observed disease associations. Where variants disrupt ...

Groups of chimpanzees within central Africa are more different genetically than humans living on different continents

Updated 02/03/2012

The study published in the journal PLoS Genetics suggests that genomics can provide a valuable new tool for use in chimpanzee conservation. It has the potential to identify the population of origin of an individual chimpanzee or the provenance of a ...

Building on our inheritance: Genomic technology in healthcare

Updated 10/02/2012

A report by the Human Genomics Strategy Group.  January 2012. A new report has been released to Ministers on genomic technology, which highlights the UK's achievements in genetics research to date and recommends a series of points to ensure future ...

Scientists discover new genetic variant that increases the risk of stroke

Updated 07/02/2012

A genetic variant that increases the risk of a common type of stroke has been identified by scientists in a study published online in Nature Genetics. This is one of the few genetic variants to date to be associated with risk of stroke. Stroke is ...

Genetics study reveals how bacteria behind serious childhood disease evolve to evade vaccines

Updated 31/01/2012

Genetics has provided surprising insights into why vaccines used in both the UK and US to combat serious childhood infections can eventually fail.  Scientists at the University of Oxford and at the Centres for Disease Control and Prevention in ...

13 new regions of the genome associated with the timing of menopause discovered

Updated 23/01/2012

Menopause -- the cessation of reproductive function of the ovaries -- is a major hormonal change that affects most women when they are in their early 50s. The timing of menopause can have a huge impact on fertility, as well as influencing the risk ...

Channel 4 News film at WTCHG

Updated 12/01/2012

08/01/12 Feature on whether the NHS is ready to make the most of advances in genetic technologies includes an interview with Professor Sir John Bell of the University of Oxford, who says: "The NHS has to move now to adopt the technology it will need ...

Hidden genetic variants revealed by new computational technique

Updated 12/01/2012

Nearly all our cells contain two copies of every chromosome, one from each parent.  Detecting the differences between the two and how they compare with the genomes of the rest of our species, is of fundamental importance to medical genetics. ...